Injection of collagenase Injection of collagenase

Injection Therapy for Peyronie’s Disease.

Collagenase clostridium histolyticum is a medication which is used to treat Peyronie’s Disease.

  • Duration:
    30 min
  • Sessions:
    2 sessions

INJECTION THERAPY FOR PEYRONIE’S DISEASE

Collagenase clostridium histolyticum is a medication which is used to treat certain conditions that are caused by a certain protein (collagen) in your body.

It treats a condition called Peyronie’s disease in adult men. This condition causes scar tissue or “plaque” to develop under the skin of the penis, resulting in an abnormal curving of the penis during erection.

Collagen is a tough and strong substance and is found in the plaques in the penis in Peyronie’s disease. Collagenase is a substance (enzyme) that breaks down the collagen in these plaques.

Peyronie's disease Peyronie's disease Normal Normal

HOW IT WORKS

Collagenase clostridium histolyticum is injected directly into the plaque of the penis. Our urologist will give you this injection.

Collagenase clostridium histolyticum is usually given in a treatment cycle of 2 injections given 1 to 3 days apart.

Your penis may need to be wrapped in a bandage for a short time after each injection. Follow your doctor’s instructions about how long to wear the bandage.

One to 3 days after your second injection, your doctor will perform a stretching procedure to help straighten the curve in your penis.

You may also need to perform gentle exercises to stretch and straighten the penis at home every day for 6 weeks. Carefully follow all directions about how to perform these exercises.

You should not have any sexual activity for at least 4 weeks after your injections.

Benefits

This medication is used to treat Peyronie’s disease.

Collagen is a tough and strong substance and is found in the plaques of the penis. Collagenase breaks down the collagen in these plaques.

Risks

Collagenase clostridium histolyticum may also damage the erectile tissues inside a man’s penis, which could require surgery to correct. Call your doctor right away if you have:

  • Bruising and swelling of your penis.
  • Pain when you urinate, blood in the urine.
  • Sudden erection problems.
  • A “popping” sound or sensation in your penis during an erection.
  • In a rare occasion (less than 1%) a penile fracture could occur in the days or weeks following injection, which requires immediate medical attention.
  • If you experience a sudden pain and significant bruising please present to your local emergency room. Surgical intervention may be required.

COMPREHENSIVE UROLOGICAL CARE AT YOUR FINGERTIPS

We pride ourselves on our compassionate and approachable nature. We understand the need to take the time to explain complex medical conditions in simple terms to ensure that you and your family are properly informed throughout your patient journey.

Book a consultation with Dr. Steinberg online or call us at 514-312-2821.

Injection of collagenase CAN BE ONE OF THE EFFICIENT TOOLS TO DIAGNOSE THE FOLLOWING CONDITIONS

Condition

Peyronie’s disease

PROCEDURE INFO

Collagenase clostridium histolyticum is injected directly into the plaque of the penis. Our urologist will give you this injection.

Your penis may need to be wrapped in a bandage for a short time after each injection. Follow your doctor’s instructions about how long to wear the bandage.

You may feel a slight pinch but the injections are virtually painless.

Collagenase clostridium histolyticum is usually given in a treatment circles of up to 7 days apart and usually 4 circles is required for a total of 8 circles. Treatment is 30 minutes long.

Although Collagenase clostridium histolyticum is not uncomfortable to receive, some patients have significant pain for up to 48 hours after the injection, with rare patients having discomfort beyond this period.

Collagenase clostridium histolyticum may also damage the erectile tissues inside a man’s penis, which could require surgery to correct. Call your doctor right away if you have:

  • Bruising and swelling of your penis;
  • Pain when you urinate, blood in the urine;
  • Sudden erection problems; or
  • A “popping” sound or sensation in your penis during an erection.

Also call your doctor immediately if you have:

  • Signs of infection such as fever, chills, redness or swelling.
  • Severe pain, itching, or other irritation.
  • Feeling like you might pass out (even while lying down).

Collagenase clostridium histolyticum
If you are unable to reach your doctor, please present yourself at the emergency center.

You may need to perform gentle exercises to stretch and straighten the penis at home every day for 6 weeks. Carefully follow all directions about how to perform these exercises.

You should not have any sexual activity for at least 4 weeks after your injections.

Your doctor may also prescribe a penile traction device to be used after injection.

FAQ

What happens if I overdose?

Since Collagenase clostridium histolyticum is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid before and after receiving Collagenase clostridium histolyticum?

Avoid sexual activity during your treatment. Your doctor will tell you when it is safe to resume sexual activity.

What other drugs can affect Collagenase clostridium histolyticum?

Other drugs may interact with collagenase clostridium histolyticum, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

The images and/or videos are not presented as a guarantee of result. The results may vary. Patients gave their consent for the publication of images and/or videos.

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At Steinberg Urology we pride ourselves on our compassionate care we offer to those facing challenges that affect their quality of life. Our urologists have years of experience and a commitment to excellence.

If you need to discuss this sensitive medical concern, schedule a consultation at our clinic in a safe confidential environment. Let us help you achieve optimal health and wellness in a professional setting.

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